Understanding how gut bacteria affect diabetic foot ulcers
Official title: The Role of the Microbiome in Diabetic Foot Ulcers
Funded at University of Michigan at Ann Arbor · NIH-11096709 · Data updated 2026-11-12
This study is looking at how the bacteria in our bodies might help or hurt the healing of diabetic foot ulcers, and it's for people with diabetes who want to learn more about improving their wound healing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 15, 2022 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $189,000 |
| NIH project number | 3K23DK131261-03S1 |
| Project ID | NIH-11096709 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with diabetic foot ulcers.
✕Less likely to help
Patients without diabetic foot ulcers or those with other unrelated conditions may not benefit from this research.
What this research studies
This research investigates the role of the microbiome, which includes the bacteria living in and on our bodies, in the healing process of diabetic foot ulcers (DFUs). By analyzing the genetic material of these bacteria, the study aims to identify factors that may hinder or promote healing in DFUs. The approach involves collecting samples from patients with DFUs to better understand how these microorganisms influence wound healing. The goal is to find new ways to improve treatment outcomes for patients suffering from this serious complication of diabetes.
Why it matters
Potential benefit: If successful, this research could lead to improved healing strategies for diabetic foot ulcers, potentially reducing the need for amputations and improving patient quality of life.
How similar studies have gone: Previous studies have suggested a link between the microbiome and wound healing, but this research aims to address design limitations and provide more definitive insights.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Schmidt, Brian M — University of Michigan at Ann Arbor
- Study coordinator: Schmidt, Brian M
Related research
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-
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-
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-
Wound fluid test to predict healing in diabetic foot ulcers
This project looks for chemical signals in the fluid from diabetic foot ulcers that could tell adults with diabetes whether a wound will heal with standard care or need a different treatment.
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MTX-001 for healing diabetic foot ulcers in people with diabetes
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.