Understanding how groups of neurons work together in the auditory system
Official title: Structure and Function of Coordinated Activity in the Auditory System
Funded at University of California, San Francisco · NIH-11072841 · Data updated 2026-11-12
This study is looking at how groups of tiny brain cells in mice work together to understand sounds and how this affects their behavior, using special tools to see how these cells change when they learn new things.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $693,856 |
| NIH project number | 1R01DC021595-01A1 |
| Project ID | NIH-11072841 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with auditory processing disorders or related neurological conditions.
✕Less likely to help
Patients with no auditory processing issues or those who are not affected by auditory system dysfunction may not receive any benefit from this research.
What this research studies
This research investigates the coordinated activity of small groups of neurons in the auditory system, focusing on how these neural ensembles process sound and influence behavior. By using advanced techniques like high-channel-count electrophysiology and optogenetics in awake mice, the study aims to uncover the structure and function of these neural networks. The research will explore how different types of neurons contribute to auditory processing and how these networks adapt during learning and task performance.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of auditory processing, potentially benefiting patients with hearing impairments or auditory processing disorders.
How similar studies have gone: Previous research has shown success in understanding neuronal processing through similar approaches, but this specific investigation into coordinated neural ensembles in the auditory system is relatively novel.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Hasenstaub, Andrea Rayne — University of California, San Francisco
- Study coordinator: Hasenstaub, Andrea Rayne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.