Understanding how groups of genes are regulated in birds
Official title: Intra- and inter-cluster regulations of multiplex gene clusters
Funded at University of Southern California · NIH-10918148 · Data updated 2026-11-12
This study is looking at how groups of related genes work together in birds' skin development, and it aims to understand how these genes are organized and communicate, which could help us learn more about gene regulation in many different species, including humans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | September 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $412,500 |
| NIH project number | 5R35GM150714-02 |
| Project ID | NIH-10918148 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with genetic disorders linked to gene regulation or those interested in developmental biology.
✕Less likely to help
Patients with conditions unrelated to gene regulation or those not affected by genetic disorders may not receive direct benefits from this research.
What this research studies
This research investigates the regulation of gene clusters, which are groups of related genes that work together within the genome. By focusing on avian skin development, the study aims to uncover the mechanisms that control how these gene clusters interact and function. The researchers will explore the epigenetic and structural aspects of gene clusters, looking at how they are organized within the cell nucleus and how they communicate with each other. This work could provide insights into gene regulation that may be applicable across various species, including humans.
Why it matters
Potential benefit: If successful, this research could lead to advancements in understanding genetic disorders and developmental diseases related to gene regulation.
How similar studies have gone: Previous research has shown success in understanding gene regulation through similar approaches, particularly in model organisms, suggesting a promising avenue for this investigation.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Liang, Ya-Chen — University of Southern California
- Study coordinator: Liang, Ya-Chen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.