Understanding how gonorrhea bacteria interact to cause infection
Mapping Protein Interaction Networks Essential for Gonococcal Pathogenesis
This study is looking at how the gonorrhea bacteria interact with proteins in order to find new ways to treat infections, especially as antibiotics become less effective.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11073023 on NIH RePORTER |
What this research studies
This research investigates the protein interaction networks of Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, to understand how it survives and causes infection in humans. By analyzing these interactions, the study aims to identify unique protein complexes that are essential for the bacteria's pathogenicity but not found in other bacteria. This could lead to new therapeutic targets, especially in light of rising antibiotic resistance. The research employs advanced biological techniques to map these interactions and their implications for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with gonorrhea, especially those with antibiotic-resistant infections.
Not a fit: Patients who do not have gonorrhea or are not affected by antibiotic-resistant strains may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new treatments for gonorrhea, particularly against antibiotic-resistant strains.
How similar studies have performed: Other research has shown promise in understanding bacterial pathogenesis through protein interaction mapping, suggesting potential for success in this approach.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Emili, Andrew — Oregon Health & Science University
- Study coordinator: Emili, Andrew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.