Understanding how glycosaminoglycans are formed in cells
Official title: Investigating the molecular mechanisms of glycosaminoglycan assembly
Funded at University of Georgia · NIH-11092278 · Data updated 2026-11-12
This study is looking at how certain sugars made by our cells, called glycosaminoglycans, are produced and how they help our cells communicate and grow, which could give us important clues about health and diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | July 15, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $377,500 |
| NIH project number | 5R35GM150736-03 |
| Project ID | NIH-11092278 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that may involve dysregulation of glycosaminoglycan function, such as certain cancers or developmental disorders.
✕Less likely to help
Patients with conditions unrelated to glycosaminoglycan metabolism or function may not benefit from this research.
What this research studies
This research aims to uncover the complex processes involved in the production of glycosaminoglycans (GAGs), which are essential carbohydrates found on all animal cells. By studying the enzymes responsible for GAG biosynthesis, the research will explore how these molecules influence cell signaling and development. The project will utilize advanced techniques to analyze the structure and function of GAGs, providing insights into their role in various cellular processes and how they can affect health and disease.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases related to cell signaling and tissue development.
How similar studies have gone: While the specific mechanisms of glycosaminoglycan assembly are still being explored, previous research has shown that understanding carbohydrate biosynthesis can lead to significant advancements in treating related diseases.
Where this research is happening
-
University of Georgia
Athens, United States Active
Researchers
- Principal investigator: Weiss, Ryan Joseph — University of Georgia
- Study coordinator: Weiss, Ryan Joseph
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.