Understanding how glycan and protein combinations affect cell communication
Capturing the Holistic Glycocode through Systems Glycobiology
['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-11128813
This study is exploring how sugars and proteins on cell surfaces work together to help our cells communicate, which could lead to better understanding of health and diseases that affect patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11128813 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between glycan and protein biomolecules at the cell surface, which play a crucial role in cellular communication and biological processes. By developing new technologies, including advanced mass spectrometry and chemical glycoproteomics, the project aims to capture and analyze the unique patterns formed by these combinations. This approach will help to overcome existing challenges in studying the glycocode, which is vital for understanding various biological functions and disease mechanisms. Patients may benefit from insights gained into how these interactions influence health and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by cellular communication, such as cancer or autoimmune diseases.
Not a fit: Patients with conditions unrelated to glycan-protein interactions or those not affected by cellular communication may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic and therapeutic strategies by enhancing our understanding of cellular communication mechanisms.
How similar studies have performed: Other research has shown promising results in understanding glycan-protein interactions, indicating that this approach could yield valuable insights.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RILEY, NICHOLAS M — UNIVERSITY OF WASHINGTON
- Study coordinator: RILEY, NICHOLAS M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.