Understanding how glucose transport is regulated in metabolic syndrome

Who could benefit from this research

What this research studies

This research investigates the mechanisms by which insulin regulates glucose uptake in muscle and fat cells, focusing on the role of a protein called TUG in the trafficking of GLUT4 glucose transporters. By examining how insulin triggers the movement of these transporters to the cell surface, the study aims to uncover the disruptions that lead to insulin resistance and metabolic syndrome. Patients may benefit from insights into how their bodies manage glucose, which could inform new treatment strategies for conditions like type 2 diabetes.

Why it matters

Where this research is happening

• Yale University
  New Haven, United States Active

Researchers

• Principal investigator: Bogan, Jonathan — Yale University
• Study coordinator: Bogan, Jonathan

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.