Understanding how gliomas maintain their telomeres
IMAGING TELOMERE MAINTENANCE MECHANISMS IN GLIOMAS
This study is looking at how brain tumors called gliomas keep themselves growing and surviving, and it aims to find special markers that can be spotted with non-invasive imaging to help track how the tumors are doing and how well treatments are working, ultimately hoping to improve care for patients with gliomas.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10756967 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that gliomas, a type of brain tumor, use to maintain their telomeres, which are crucial for their growth and survival. The study aims to identify specific metabolic biomarkers that can be detected through non-invasive imaging techniques, allowing for better monitoring of tumor progression and response to treatments. By using advanced magnetic resonance spectroscopy (MRS), researchers will analyze glioma cells and animal models to uncover unique metabolic signatures associated with telomere maintenance mechanisms. This could lead to improved diagnostic and therapeutic strategies for patients with gliomas.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with gliomas, including both high-grade and low-grade variants.
Not a fit: Patients with tumors other than gliomas or those without active disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new ways to monitor glioma progression and treatment response, potentially leading to more effective therapies.
How similar studies have performed: Previous research has shown promise in using metabolic imaging techniques for cancer monitoring, suggesting that this approach could be effective for gliomas as well.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Viswanath, Pavithra — University of California, San Francisco
- Study coordinator: Viswanath, Pavithra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.