Understanding how glioblastoma responds to drugs
Pharmacologic and Genomic Imaging Core
This study is looking at how different parts of glioblastoma tumors and how drugs spread within them can change how well treatments work, with the hope of finding better ways to help patients with this type of brain cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10911183 on NIH RePORTER |
What this research studies
This research investigates the complex nature of glioblastoma, focusing on how variations in tumor composition and drug distribution affect treatment responses. By utilizing advanced imaging techniques and patient-derived models, the study aims to assess how genetic and environmental factors influence the effectiveness of drug candidates. The goal is to improve our understanding of drug interactions within the tumor microenvironment, which could lead to more effective treatment strategies for patients with glioblastoma.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma or glioblastoma multiforme.
Not a fit: Patients with other types of brain tumors or those not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with glioblastoma.
How similar studies have performed: Other research has shown promise in using advanced imaging and genomic techniques to improve treatment outcomes for glioblastoma, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Suva, Mario Luca — Brigham and Women's Hospital
- Study coordinator: Suva, Mario Luca
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.