Understanding how glioblastoma interacts with brain environments through tiny vesicles
GLIOMA INTERACTION WITH THE NEUROGENIC NICHE THROUGH EXTRACELLULAR VESICLES
['FUNDING_R21'] · MAYO CLINIC JACKSONVILLE · NIH-10999368
This study is looking at how an aggressive brain tumor called glioblastoma interacts with its surroundings and how tiny particles released by cells might affect the tumor's growth, with the hope of finding new ways to improve treatment for patients like you.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC JACKSONVILLE (nih funded) |
| Locations | 1 site (JACKSONVILLE, UNITED STATES) |
| Trial ID | NIH-10999368 on ClinicalTrials.gov |
What this research studies
This research investigates the aggressive brain tumor glioblastoma (GBM) and its interaction with the neurogenic niche, particularly focusing on how extracellular vesicles influence tumor behavior. By examining the relationship between GBM and the surrounding brain structures, the study aims to uncover mechanisms that contribute to tumor growth and recurrence. Patients may benefit from insights that could lead to new therapeutic strategies targeting these interactions, potentially improving treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults diagnosed with glioblastoma, particularly those with tumors near the lateral ventricles.
Not a fit: Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that reduce glioblastoma recurrence and improve patient survival rates.
How similar studies have performed: Previous research has shown promising results in understanding tumor interactions with the neurogenic niche, indicating potential for breakthroughs in treatment.
Where this research is happening
JACKSONVILLE, UNITED STATES
- MAYO CLINIC JACKSONVILLE — JACKSONVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GUERRERO-CAZARES, HUGO — MAYO CLINIC JACKSONVILLE
- Study coordinator: GUERRERO-CAZARES, HUGO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.