Understanding how glioblastoma cells spread in the brain
Cellular and Molecular Mechanisms of GBM Infiltration
This study is looking into how glioblastoma, a tough brain tumor, spreads in the brain and how it comes back after treatment, with the hope of finding better ways to stop it from spreading and improve care for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11061292 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind the spread of glioblastoma (GBM), a highly aggressive brain tumor. It focuses on how GBM cells migrate throughout the brain, often leading to recurrence after treatment. By analyzing tumor samples and studying the interaction between GBM cells and neurons, the research aims to identify specific genes and immune responses involved in this infiltration process. Patients may benefit from insights that could lead to improved treatment strategies targeting GBM spread.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma who are undergoing treatment or have recently had surgery.
Not a fit: Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that prevent the spread of glioblastoma, potentially improving survival rates for patients.
How similar studies have performed: Previous studies have shown promising results in understanding tumor infiltration mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Deneen, Benjamin — Baylor College of Medicine
- Study coordinator: Deneen, Benjamin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.