Understanding how glioblastoma affects brain activity and vice versa
RECIPROCAL FEEDBACK MECHANISMS OF GLIOBLASTOMA AND NEURONAL NETWORK HYPEREXCITABILITY
This study is looking at how glioblastoma, a type of brain cancer, affects brain activity and causes seizures, with the hope of finding new ways to slow down the tumor and help improve the lives of patients dealing with both the cancer and epilepsy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11019752 on NIH RePORTER |
What this research studies
This research investigates the complex relationship between glioblastoma, a type of brain cancer, and tumor-related epilepsy, which affects many patients with this condition. By using advanced imaging techniques and genetic models, the study aims to uncover how glioblastoma cells influence brain activity and how this interaction can lead to tumor growth. The goal is to identify potential therapeutic windows that could be targeted to slow down tumor progression and improve the quality of life for patients suffering from seizures. This approach is innovative as it combines cellular imaging with genetic manipulation to explore these mechanisms in a living organism.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma who are experiencing tumor-related epilepsy.
Not a fit: Patients with glioblastoma who do not experience seizures or those with other types of brain tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that not only slow glioblastoma progression but also enhance the quality of life for patients by reducing seizure occurrences.
How similar studies have performed: Previous research has shown promising results in understanding the interactions between glioblastoma and neuronal activity, suggesting that this approach could yield significant insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Meyer, Jochen — Baylor College of Medicine
- Study coordinator: Meyer, Jochen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.