Understanding how glial cells stabilize brain function
Stabilizing Brain Function via Glial Epigenetic Signaling
['FUNDING_R01'] · GEORGETOWN UNIVERSITY · NIH-10883688
This study is looking at how certain brain cells, called glial cells, help keep our brain working well and how problems with these cells might lead to conditions like Alzheimer's and autism, with the hope of finding new ways to treat these issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGETOWN UNIVERSITY (nih funded) |
| Locations | 1 site (WASHINGTON, UNITED STATES) |
| Trial ID | NIH-10883688 on ClinicalTrials.gov |
What this research studies
This research investigates the role of glial cells in maintaining stable brain function and behavior by examining their signaling mechanisms. It focuses on how defects in these signaling pathways can lead to chronic neurological disorders such as Alzheimer's disease and autism. By using genetic models, the research aims to uncover the epigenetic processes that glial cells use to regulate neurotransmitter release and synaptic stability. Patients may benefit from insights gained into potential new therapeutic targets for these conditions.
Who could benefit from this research
Good fit: Ideal candidates include individuals diagnosed with Alzheimer's disease, autism spectrum disorders, or other related neurological conditions.
Not a fit: Patients with acute neurological injuries or those without chronic neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve brain function and quality of life for patients with neurological disorders.
How similar studies have performed: Other research has shown promising results in understanding glial cell functions, but this specific approach to epigenetic signaling in glial cells is relatively novel.
Where this research is happening
WASHINGTON, UNITED STATES
- GEORGETOWN UNIVERSITY — WASHINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, TINGTING — GEORGETOWN UNIVERSITY
- Study coordinator: WANG, TINGTING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease