Understanding how glial cells interact with nerve cells in the brain
Mechanisms of Glial Interactions and Function at Neuronal Cell Bodies
This study is looking at how support cells in the brain, called glial cells, help keep nerve cells healthy and working well, using fruit flies to learn more about their important roles in brain health and diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-11051777 on NIH RePORTER |
What this research studies
This research investigates the interactions between glial cells and neuronal cell bodies in the central nervous system, focusing on how these interactions support neuronal health and function. Using advanced genetic tools in Drosophila, a model organism, the study aims to uncover the mechanisms of glial development and communication. By examining how glial cells provide metabolic support, regulate ion balance, and respond to neuronal signals, the research seeks to fill knowledge gaps about glial roles in brain health and disease. This could lead to insights into how glial dysfunction contributes to neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions that may involve glial dysfunction.
Not a fit: Patients with purely peripheral nervous system disorders or those without neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain health and lead to new therapeutic strategies for neurological disorders.
How similar studies have performed: Other research has shown promising results in understanding glial interactions in various contexts, suggesting that this approach could yield valuable insights.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Coutinho-Budd, Jaeda — University of Virginia
- Study coordinator: Coutinho-Budd, Jaeda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.