Understanding how Giardia affects gut healing
Intestinal Barrier Repair Mechanisms in Giardiasis
This study is looking at how the Giardia parasite affects the gut and what helps it heal afterward, so we can better understand the long-term health problems it can cause for people who get infected.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-10903020 on NIH RePORTER |
What this research studies
This research investigates the effects of the Giardia parasite on the intestinal barrier, which is crucial for nutrient absorption. It focuses on how Giardia infection leads to damage in the gut and explores the mechanisms that help repair this damage. Using a mouse model, the study aims to uncover how the gut microbiome's metabolites influence the healing process after infection. By understanding these repair dynamics, the research seeks to provide insights into long-term health issues associated with Giardiasis.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and individuals who have experienced Giardiasis or are at risk of infection.
Not a fit: Patients who have not been infected with Giardia or those with unrelated gastrointestinal disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for Giardiasis and better management of its long-term effects on gut health.
How similar studies have performed: Previous research has shown promising results in understanding gut microbiome interactions, but this specific approach to barrier repair in Giardiasis is relatively novel.
Where this research is happening
Washington, United States
- Georgetown University — Washington, United States (Active)
Researchers
- Principal investigator: Kosile, Rita Taye — Georgetown University
- Study coordinator: Kosile, Rita Taye
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.