Understanding how germs become resistant to antibiotics and how viruses infect cells
Biophysical studies of macromolecules and molecular assemblies
This work explores new ways to understand the tiny parts of cells and viruses to help us fight infections and antibiotic resistance.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11127768 on NIH RePORTER |
What this research studies
Our team is developing advanced physical methods to look closely at biological systems, helping us understand complex processes. We are particularly focused on two major health challenges: figuring out why bacteria become resistant to antibiotics and understanding how viruses enter our cells. By using specialized tools like vibrational Stark effect spectroscopy, we can measure the electrical forces at work in enzymes, which helps us learn how they function. This detailed understanding could lead to new strategies against infections.
Who could benefit from this research
Good fit: This foundational laboratory research does not involve direct patient participation but aims to benefit future patients by informing new drug development.
Not a fit: Patients seeking immediate treatment or direct clinical intervention would not receive benefit from this basic science research.
Why it matters
Potential benefit: If successful, this fundamental understanding could pave the way for new treatments to overcome antibiotic resistance and prevent viral infections.
How similar studies have performed: The research builds upon four years of accomplishments and has led the development of advanced spectroscopic methods, indicating a track record of success in similar approaches.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Boxer, Steven G. — Stanford University
- Study coordinator: Boxer, Steven G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.