Understanding how genetics influence obesity and its treatment
From Obesity GWAS to therapeutic targets
This study is looking at how our genes might play a role in obesity and aims to find new ways to help people manage their weight by understanding how certain parts of the brain control eating and body weight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10866441 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to obesity and how these factors can be targeted for therapeutic purposes. By analyzing genetic variations linked to obesity, the study aims to identify specific regulatory regions in the brain that control food intake and body weight. Utilizing advanced techniques like CRISPR and ATAC sequencing, researchers will explore the mechanisms behind obesity at a molecular level, potentially leading to new treatment strategies. Patients may benefit from insights that could lead to personalized interventions for obesity-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a genetic predisposition to obesity or those struggling with obesity-related health issues.
Not a fit: Patients who are not affected by obesity or do not have a genetic component to their weight issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, targeted therapies for obesity and its associated health risks.
How similar studies have performed: Previous research has shown promising results in understanding genetic influences on obesity, making this approach both relevant and potentially impactful.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Vaisse, Christian — University of California, San Francisco
- Study coordinator: Vaisse, Christian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.