Understanding how genetics and environment affect type 2 diabetes in people of African descent
Unravelling the Role of Epigenetics and Cytokines in Type 2 Diabetes among African-ancestry Populations
This study is looking at how different factors, like genetics and lifestyle choices, affect the risk of developing type 2 diabetes in people of African descent, with the goal of finding ways to help prevent the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11221677 on NIH RePORTER |
What this research studies
This research investigates the complex factors contributing to type 2 diabetes (T2D) among African-ancestry populations, focusing on the roles of epigenetics and cytokines. It aims to understand how genetic variations and lifestyle factors, such as diet and alcohol consumption, interact to influence the risk of developing T2D. The study employs advanced methodologies, including causal inference and multi-omics analysis, to explore these relationships and identify potential biological mechanisms. By examining DNA methylation and circulating cytokine levels, the research seeks to uncover insights that could lead to targeted interventions for affected populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals of African ancestry who are at risk for or currently living with type 2 diabetes.
Not a fit: Patients of non-African ancestry or those without risk factors for type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for type 2 diabetes specifically tailored for individuals of African descent.
How similar studies have performed: Previous research has shown promising results in understanding the genetic and environmental factors influencing type 2 diabetes in diverse populations, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Meeks, Karlijn Anna Catharina — University of Maryland Baltimore
- Study coordinator: Meeks, Karlijn Anna Catharina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.