NIH-funded research R01 grant

Understanding how genetics and environment affect ADHD from childhood to adolescence

Official title: Polygenic and environmental contributions to ADHD trajectory and outcome from childhood through adolescence

Funded at Oregon Health & Science University · NIH-10999305 · Data updated 2026-11-12

This study looks at how ADHD develops from childhood to late teens by exploring both genetic and environmental influences, like family and neighborhood, to better understand what affects ADHD symptoms and how to help those who have it.

More ADHD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startFebruary 1, 2023
Project endNovember 30, 2027
Funding year2025
Award (this year)$638,719
NIH project number5R01MH131685-03
Project IDNIH-10999305 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children and adolescents aged 0-20 who are diagnosed with ADHD or exhibit related symptoms.

Less likely to help

Patients who are outside the age range of 0-20 or do not have a diagnosis of ADHD may not benefit from this research.

What this research studies

This research investigates the development of ADHD and its related behaviors from childhood through late adolescence. It combines genetic information and environmental factors, such as neighborhood conditions and family influences, to understand how these elements contribute to ADHD symptoms and outcomes. By analyzing data from large groups of youth, the study aims to identify patterns and risk factors that influence ADHD trajectories over time. This comprehensive approach may help in tailoring interventions for affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for ADHD, potentially enhancing the quality of life for affected individuals.

How similar studies have gone: Previous research has shown promise in understanding ADHD through genetic and environmental factors, indicating that this approach could yield valuable insights.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Mooney, Michael a — Oregon Health & Science University
  • Study coordinator: Mooney, Michael a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.