Understanding how genetics and cognitive skills affect recovery from language therapy after a stroke
Laying the Groundwork for Personalized Medicine in Aphasia Therapy: Genetic an Cognitive Predictors of Restorative Treatment Response
['FUNDING_R01'] · OHIO STATE UNIVERSITY · NIH-10693204
This study is looking at how your genes and thinking skills can affect how well language therapy works for people recovering from aphasia after a stroke, so we can create more personalized treatment plans that help you recover better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-10693204 on ClinicalTrials.gov |
What this research studies
This research investigates how specific genetic factors and cognitive abilities influence the effectiveness of language therapy for individuals recovering from aphasia after a stroke. By examining the relationship between certain genes, such as ApoE and BDNF, and cognitive skills like working memory, the study aims to identify which patients are likely to benefit most from targeted therapy approaches. The goal is to personalize treatment plans based on these patient-specific factors, ultimately improving recovery outcomes. Participants may undergo assessments to evaluate their genetic makeup and cognitive functions to better tailor their therapy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a stroke and are diagnosed with aphasia, particularly those interested in personalized treatment approaches.
Not a fit: Patients who have not had a stroke or do not have aphasia may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized language therapy for stroke survivors with aphasia.
How similar studies have performed: While the role of genetics in language recovery is a relatively novel area of research, preliminary studies suggest that genetic factors may influence treatment outcomes in other rehabilitation contexts.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HARNISH, STACY M — OHIO STATE UNIVERSITY
- Study coordinator: HARNISH, STACY M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.