Understanding how genetics and brain structure contribute to neuropsychiatric conditions like autism

Estimating The Fraction of Variance Explained by Genetics and Neuroanatomy in Neuropsychiatric Conditions

NIH-funded research University of California, San Diego · NIH-10875541

This study is looking at how our genes and brain structure might influence autism, with the goal of finding better ways to diagnose and treat people with the condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-10875541 on NIH RePORTER

What this research studies

This research investigates the role of genetics and neuroanatomy in neuropsychiatric conditions, particularly autism. By analyzing high-dimensional biomarkers, the study aims to quantify how much these factors contribute to the risk and manifestation of such disorders. The approach includes utilizing advanced techniques like Genome-Wide Association Studies (GWAS) and neuroimaging to gather and assess data. This could lead to better diagnostic tools and treatment strategies for affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with autism or related neuropsychiatric conditions, particularly adolescents.

Not a fit: Patients with neuropsychiatric conditions not related to autism may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted treatments for neuropsychiatric conditions, enhancing patient outcomes.

How similar studies have performed: Previous research using similar methodologies, such as GWAS and neuroimaging, has shown promise in understanding the biological underpinnings of mental health disorders.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.