Understanding how genetics affects blood cell traits
Next generation functional genomics of hematology traits
This study is looking at how our genes affect things like red blood cell counts and hemoglobin levels, which can help us understand blood disorders better and improve care for people with these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11134527 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that influence red blood cell traits and non-malignant blood disorders. By analyzing large datasets from diverse populations, the project aims to identify genetic variants that affect blood cell characteristics such as hemoglobin levels and red blood cell counts. The study employs advanced statistical and computational methods to uncover rare and ancestry-specific genetic variants, enhancing our understanding of how these variants function. Ultimately, the goal is to translate these findings into clinical applications that can improve patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with varying ancestry who have red blood cell disorders or traits.
Not a fit: Patients with blood disorders that are not influenced by genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for blood disorders, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding genetic influences on blood traits, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Reiner, Alexander P — University of Washington
- Study coordinator: Reiner, Alexander P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.