Understanding how genetics affects asthma in different lung cells
Genetics of Asthma Sub-Phenotypes Impact Gene Regulation in Cell-Specific Patterns
This study is looking at how our genes might affect asthma by checking how certain lung cells behave, and it's for anyone interested in understanding the different ways asthma can show up in people.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10892696 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that influence asthma by examining how gene expression varies in specific lung cell types. The project aims to identify genetic variations that contribute to different asthma sub-phenotypes, which can help in understanding the disease's complexity. By utilizing advanced techniques in genetics and immunology, the research will explore the relationship between genetic risk factors and the biological mechanisms underlying asthma. This work is being conducted at the University of Chicago under the guidance of experienced mentors.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a diagnosis of asthma, particularly those with varying ages of onset and different asthma subtypes.
Not a fit: Patients with asthma who do not have a genetic component to their condition or those without a clear asthma diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for asthma based on individual genetic profiles.
How similar studies have performed: Previous research has shown promise in understanding genetic influences on asthma, indicating that this approach could yield valuable insights.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Schoettler, Nathan R — University of Chicago
- Study coordinator: Schoettler, Nathan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.