Understanding how genetics affect pregnancy outcomes and later health issues
Integrating genomic studies of gestational duration and birth weight to understand maternal and fetal causes of adverse pregnancy outcomes and links with later diseases
['FUNDING_R01'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10825442
This study is looking at how genes from both moms and babies affect how long a pregnancy lasts and how much the baby weighs at birth, with the goal of helping improve prenatal care for healthier outcomes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-10825442 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic factors influencing gestational duration and birth weight, which are critical indicators of pregnancy outcomes. By integrating genomic studies, the team aims to understand how maternal and fetal genetics contribute to these outcomes and their links to later health conditions. The approach includes large-scale genome-wide association studies and novel statistical methods to analyze the genetic effects on birth outcomes. Patients may benefit from insights that could lead to improved prenatal care and interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals and their offspring, particularly those with concerns about gestational duration or birth weight.
Not a fit: Patients who are not pregnant or do not have a history of complications related to gestational duration or birth weight may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of adverse pregnancy outcomes and related health issues in children and adults.
How similar studies have performed: Previous genomic studies have shown success in identifying genetic factors related to gestational duration and birth weight, but this integrated approach is relatively novel.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHANG, GE — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: ZHANG, GE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.