Understanding how genetics affect drug responses
PharmGKB
This study is all about understanding how our genes can affect how well medications work for us, and it's designed to help doctors find the best treatments for patients by using a new resource that shares important information about these genetic differences.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11004084 on NIH RePORTER |
What this research studies
This research focuses on pharmacogenomics, which examines how genetic differences among individuals influence their responses to medications. By creating a comprehensive public resource known as the Pharmacogenomics Knowledgebase (PharmGKB), the project aims to gather and share critical information about genetic variations that affect drug efficacy and safety. This resource will support both basic research into the mechanisms of drug response and clinical applications, helping healthcare providers choose the right medications for patients based on their genetic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are prescribed medications and may benefit from tailored drug therapies based on their genetic makeup.
Not a fit: Patients who do not take medications or have no genetic variations affecting drug responses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective medication treatments for patients, minimizing adverse drug reactions and improving therapeutic outcomes.
How similar studies have performed: Previous research in pharmacogenomics has shown promise in improving drug response and safety, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Klein, Teri Ellen — Stanford University
- Study coordinator: Klein, Teri Ellen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.