Understanding how genetics affect drug metabolism in American Indian and Alaska Native people
Pharmacogenomic approaches to drug metabolism in American Indian/Alaska Native People
This study is looking at how your genes can affect how well certain medications work for you, especially for American Indian and Alaska Native communities, so that treatments can be safer and more effective just for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10876941 on NIH RePORTER |
What this research studies
This research focuses on pharmacogenetic testing to improve drug safety and effectiveness by personalizing treatment based on individual genetic profiles. It aims to identify genetic variations that influence how drugs are absorbed, distributed, metabolized, and excreted in American Indian and Alaska Native populations. By cataloging these genetic differences, the study seeks to enhance clinical outcomes and address the historical underrepresentation of these communities in genomic research. The research is conducted in collaboration with local tribal partners to ensure community engagement and trust.
Who could benefit from this research
Good fit: Ideal candidates for this research are American Indian and Alaska Native individuals who may benefit from personalized medication regimens.
Not a fit: Patients who do not identify as American Indian or Alaska Native may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective drug treatments tailored specifically for American Indian and Alaska Native individuals.
How similar studies have performed: Previous research has shown success in pharmacogenetic approaches in other populations, but this study aims to address a novel and underrepresented group.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Claw, Katrina G — University of Colorado Denver
- Study coordinator: Claw, Katrina G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.