Understanding how genetic variations influence traits in maize
Exploration of cis-regulatory diversity underlying phenotypic innovation
This study is looking at how differences in certain parts of DNA that don't code for proteins can influence how genes work and lead to different traits in corn, helping us understand why some corn plants look or grow differently than others.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10915712 on NIH RePORTER |
What this research studies
This research investigates how genetic variations in non-coding regions of DNA, specifically within cis-regulatory elements, affect gene transcription and contribute to the diversity of traits in maize. By analyzing a diverse panel of maize individuals, the study aims to uncover the molecular mechanisms linking these genetic variants to observable characteristics. The approach involves advanced DNA sequencing and computational analysis to map the relationships between genetic variants and their effects on cellular and organismal traits. This research could provide insights into the fundamental processes of gene regulation and phenotypic variation.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include agricultural scientists, geneticists, and farmers interested in crop improvement and genetic diversity.
Not a fit: Patients who are not involved in agricultural research or do not work with maize or similar crops may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic factors influencing crop traits, potentially leading to improved agricultural practices and crop yields.
How similar studies have performed: Other research has shown success in understanding genetic variations and their impact on phenotypes, particularly in model organisms, making this approach promising.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Marand, Alexandre — University of Michigan at Ann Arbor
- Study coordinator: Marand, Alexandre
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.