Understanding how genetic variations influence disease risk
COBRE in Human Genetics
This study is exploring how our genes and their changes can lead to both common and rare genetic diseases, and it's designed to help patients by finding better ways to understand and treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Clemson University NIH-funded |
| Lab location | 1 site (Clemson, United States) |
| Project ID | NIH-11015918 on NIH RePORTER |
What this research studies
This research investigates the genetic, genomic, and epigenetic mechanisms that contribute to both common and rare genetic diseases. By utilizing a multidisciplinary approach that includes bioinformatics, molecular genetics, and animal models, the project aims to uncover how genetic variations affect disease risk. The research will support various projects led by junior investigators, focusing on topics such as the role of long non-coding RNAs and structural variations in disease. Patients may benefit from insights gained through this research, which could lead to improved understanding and treatment of genetic conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with known genetic conditions or those at risk for genetic diseases.
Not a fit: Patients with purely environmental diseases or those without a genetic component may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic diseases and lead to better diagnostic and therapeutic strategies for patients.
How similar studies have performed: Previous research in genetic mechanisms has shown promise in understanding disease risk, indicating that this approach could yield valuable insights.
Where this research is happening
Clemson, United States
- Clemson University — Clemson, United States (Active)
Researchers
- Principal investigator: Mackay, Trudy F. — Clemson University
- Study coordinator: Mackay, Trudy F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.