Understanding how genetic variations in yeast affect their traits
EDGE CMT: Dissecting complex traits in wild isolates of yeast by high-throughput genome editing
This study is exploring how changes in yeast's genes can affect their traits and behaviors, which could help improve medicine and farming, and it's designed for anyone interested in how tiny organisms can make a big difference!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11015863 on NIH RePORTER |
What this research studies
This research investigates how different genetic variations in yeast can influence their characteristics and behaviors. By using advanced genome editing techniques, researchers will create a diverse set of yeast strains, each with specific genetic modifications. These strains will be analyzed to understand how their genetic makeup interacts with environmental factors, which could lead to breakthroughs in precision medicine and agricultural biotechnology. The study aims to identify causal genetic variants and their effects on traits in natural yeast populations.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in genetic engineering and its applications in agriculture and health.
Not a fit: Patients with no interest in genetic research or those not involved in agricultural or microbial applications may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for engineering crops and microbes, enhancing their desirable traits for agriculture and medicine.
How similar studies have performed: Other research has shown success with similar high-throughput genome editing approaches, indicating a promising avenue for further exploration.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Steinmetz, Lars M — Stanford University
- Study coordinator: Steinmetz, Lars M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.