Understanding how genetic variations contribute to diseases using advanced data analysis.
Statistical methods and analyses to study genetic variants and their roles in diseases leveraging functional genomics data.
['FUNDING_OTHER'] · DARTMOUTH COLLEGE · NIH-10939001
This study is looking at how certain genetic differences can affect diseases by using advanced data about genes, which could help us understand your genetic risks better and find new treatments just for you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DARTMOUTH COLLEGE (nih funded) |
| Locations | 1 site (HANOVER, UNITED STATES) |
| Trial ID | NIH-10939001 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying genetic variants that play a role in various diseases by utilizing large-scale functional genomics data. It aims to develop new statistical methods to analyze this data, particularly single-cell transcriptomic and epigenomic information, to uncover how these genetic variants affect gene regulation and contribute to disease mechanisms. By bridging the gap between genetic associations identified in previous studies and their functional implications, the research seeks to provide insights into the biological processes underlying diseases. Patients may benefit from a better understanding of their genetic risks and potential targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of genetic diseases or those diagnosed with conditions linked to genetic variations.
Not a fit: Patients with diseases that are not influenced by genetic factors or those without identifiable genetic variants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification of genetic risks for diseases and more personalized treatment options for patients.
How similar studies have performed: Previous research has shown success in using functional genomics data to identify genetic variants associated with diseases, indicating that this approach has potential for meaningful advancements.
Where this research is happening
HANOVER, UNITED STATES
- DARTMOUTH COLLEGE — HANOVER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHAO, SIMING — DARTMOUTH COLLEGE
- Study coordinator: ZHAO, SIMING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.