Understanding how genetic variations affect cancer traits.
MolQTL: A comprehensive resource for molecular quantitative trait loci inhuman cancer.
['FUNDING_R01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-11061263
This study is looking at how certain genetic differences can affect cancer traits, like how genes behave and change, to help patients and researchers understand how these factors might influence cancer treatment outcomes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-11061263 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying molecular quantitative trait loci (molQTLs) that link genetic variations to cancer characteristics. By analyzing a large dataset of cancer samples, the study aims to uncover how specific genetic variants influence cancer traits such as gene expression and methylation patterns. This information will be made accessible through user-friendly data portals, allowing patients and researchers to explore the connections between genetics and cancer outcomes. The ultimate goal is to enhance precision medicine by providing insights into how genetic factors can affect individual responses to cancer treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include cancer patients who are interested in understanding the genetic factors that may influence their disease and treatment responses.
Not a fit: Patients with non-cancerous conditions or those not interested in genetic research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective cancer treatments based on individual genetic profiles.
How similar studies have performed: Previous research has successfully utilized similar approaches to link genetic variants with disease traits, indicating a promising avenue for further exploration.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAN, LENG — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: HAN, LENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anti-Cancer Agents, anti-cancer drug, Cancer Drug, cancer type, Cancers