Understanding how genetic variations affect blood pressure regulation
Sequencing Coordination and Data Analysis Core
This study is looking at how certain hidden parts of our DNA might affect blood pressure, using advanced technology to understand the genetic differences in specific cells, and it aims to help improve how we manage blood pressure issues for everyone.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10903750 on NIH RePORTER |
What this research studies
This research focuses on the genetic factors that influence blood pressure by examining noncoding regions of DNA, which are often overlooked. It utilizes advanced sequencing technologies to analyze various RNA and DNA profiles in specific cell types related to blood pressure. The project aims to uncover how these genetic variations impact blood pressure regulation through a series of coordinated analyses and data interpretation. By leveraging next-generation sequencing, the research seeks to provide insights that could lead to better management of blood pressure-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of high blood pressure or those diagnosed with hypertension.
Not a fit: Patients with blood pressure issues that are solely due to lifestyle factors without any genetic predisposition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing and treating high blood pressure.
How similar studies have performed: Previous research has shown promising results using similar genetic and epigenomic approaches to understand blood pressure regulation.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Liu, Pengyuan — University of Arizona
- Study coordinator: Liu, Pengyuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.