Understanding how genetic traits evolve quickly in humans
Rapid Evolution of Genomic Architecture and Multi-omics Traits
['FUNDING_OTHER'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10676738
This study is looking at how quickly our genes can change and how those changes might affect health, especially for people with Native American ancestry, so that patients can better understand how their genetics influence their well-being.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10676738 on ClinicalTrials.gov |
What this research studies
This research investigates the rapid evolution of genetic traits using advanced sequencing and multi-omics profiling techniques. By analyzing genetic variations and mutations, the study aims to uncover how these changes affect health and disease, particularly in populations with Native American ancestry. The research includes collaborations with health institutions in Peru to evaluate the genetic dynamics of specific gene clusters related to fatty acid regulation. Patients may benefit from insights into how their genetic makeup influences health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals of Native American ancestry or those interested in genetic health assessments.
Not a fit: Patients with no genetic predisposition or interest in the evolutionary aspects of health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic factors influencing health, potentially guiding personalized medicine approaches.
How similar studies have performed: Previous research has shown success in understanding genetic variations and their health implications, making this approach both relevant and promising.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: O'CONNOR, TIMOTHY DAVID — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: O'CONNOR, TIMOTHY DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.