Understanding how genetic factors influence increased fentanyl use
Functional and Genomic Signatures of Escalated Fentanyl Use
['FUNDING_R01'] · UNIVERSITY OF KENTUCKY · NIH-11001468
This study is looking at how our genes might influence how people behave when using fentanyl, with the goal of finding better, personalized treatments for those dealing with opioid use disorder.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KENTUCKY (nih funded) |
| Locations | 1 site (LEXINGTON, UNITED STATES) |
| Trial ID | NIH-11001468 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between genetic markers and the behavioral patterns associated with escalating fentanyl use. By studying animal models, the project aims to identify how individual differences in genetics can affect responses to opioids, particularly in the context of opioid use disorder (OUD). The researchers will analyze behavioral, cellular, and genomic data to develop personalized treatment approaches that could improve outcomes for patients struggling with OUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of opioid use disorder, particularly those who have experienced escalated use of fentanyl.
Not a fit: Patients who do not have a history of opioid use or those who are not affected by opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for individuals with opioid use disorder.
How similar studies have performed: Previous research has shown promise in using genetic and behavioral approaches to tailor treatments for other conditions, suggesting potential for success in this novel area.
Where this research is happening
LEXINGTON, UNITED STATES
- UNIVERSITY OF KENTUCKY — LEXINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TURNER, JILL R. — UNIVERSITY OF KENTUCKY
- Study coordinator: TURNER, JILL R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer therapy