Understanding How Genetic Differences Affect Your Health
Technology to understand genetic variant effects in context
This project is creating new ways to understand how tiny changes in our genes can influence our health, disease risks, and how we respond to medicines.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11141034 on NIH RePORTER |
What this research studies
This project is creating advanced tools to help us understand how individual genetic differences impact our health. We know that each person has a unique genetic makeup and life experiences, which can change how a specific gene variant acts. This work will help us understand how these genetic changes work in different environments, alongside other genes, and within various body systems. The goal is to improve our ability to predict disease risks and how treatments might work for each person.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation, but its future applications could benefit anyone seeking to understand their genetic predispositions to disease or drug responses.
Not a fit: Patients who are not interested in understanding their genetic information or personalized medical approaches may not directly benefit from this specific technology development.
Why it matters
Potential benefit: If successful, this work could lead to more personalized medicine, allowing doctors to better predict disease risks and tailor treatments based on an individual's unique genetic profile.
How similar studies have performed: The researchers have already developed and used similar technologies to map the effects of millions of genetic variants, showing prior success in this area.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Fowler, Douglas M — University of Washington
- Study coordinator: Fowler, Douglas M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.