Understanding how genetic differences affect disease and evolution
Origins, Functional, and Evolutionary Consequences of Genomic Variation
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA SANTA CRUZ · NIH-11005288
This study is looking at how our genes might affect our chances of getting sick from COVID-19 and how they change over time, so we can better understand the virus and help people stay healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA SANTA CRUZ (nih funded) |
| Locations | 1 site (SANTA CRUZ, UNITED STATES) |
| Trial ID | NIH-11005288 on ClinicalTrials.gov |
What this research studies
This research investigates the role of genetic variation in evolution and disease susceptibility, particularly focusing on the SARS-CoV-2 virus. By utilizing advanced genome sequencing technologies and bioinformatics, the team aims to develop computational methods to analyze genetic relationships within populations. The research will explore how genetic isolation and adaptation occur, as well as the effects of intron variation on fitness. Patients may benefit from insights gained about genetic factors influencing COVID-19 susceptibility and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a genetic predisposition to COVID-19 or those interested in understanding their genetic risk factors.
Not a fit: Patients who do not have a genetic predisposition to COVID-19 or who are not interested in genetic research may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic factors that influence disease susceptibility, potentially leading to better prevention and treatment strategies for COVID-19.
How similar studies have performed: Previous research has shown success in using genomic analysis to understand disease susceptibility and evolutionary processes, indicating that this approach is promising.
Where this research is happening
SANTA CRUZ, UNITED STATES
- UNIVERSITY OF CALIFORNIA SANTA CRUZ — SANTA CRUZ, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CORBETT-DETIG, RUSSELL — UNIVERSITY OF CALIFORNIA SANTA CRUZ
- Study coordinator: CORBETT-DETIG, RUSSELL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: coronavirus disease 2019 virus