Understanding how genetic changes in body tissues affect health and disease

WashU Somatic Mosaicism across Human Tissues (SMaHT) Program Organizational Center

NIH-funded research Washington University · NIH-11098566

This study is looking at how changes in our genes can affect our health and aims to help researchers work together better, so they can find new ways to understand and treat different health conditions that might be linked to these gene changes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11098566 on NIH RePORTER

What this research studies

The SMaHT Network focuses on discovering new biological processes related to genomic variations in human tissues. This research aims to enhance the coordination and sharing of genomic data to better understand how these variations influence health and disease. By establishing a central organizational center, the project will facilitate collaboration among researchers and improve access to valuable genomic resources. Patients may benefit from insights gained about the role of somatic mosaicism in various conditions.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit include individuals with genetic disorders or those interested in the implications of somatic mosaicism in their health.

Not a fit: Patients with conditions unrelated to genetic variations in somatic tissues may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to new insights into disease mechanisms and potential therapeutic targets for various health conditions.

How similar studies have performed: Previous research initiatives in genomic data sharing and analysis have shown promise, suggesting that this approach could yield significant advancements in understanding human health.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer Etiology
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.