Understanding how genetic changes affect disease risk and adaptation in humans.
Evolution on epidemiologically-relevant timescales
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11010730
This study looks at how humans have changed genetically over the last 10,000 years, especially in response to farming and new diseases, to help people understand how their unique genetic backgrounds might affect their health and risk for certain diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11010730 on ClinicalTrials.gov |
What this research studies
This research investigates the ongoing process of evolution and its impact on human genetic variation, particularly in relation to disease risk and adaptation to new environments. By utilizing advanced computational methods and theoretical models, the project aims to analyze how populations have evolved over the last 10,000 years, especially in response to agriculture and emerging diseases. The research focuses on admixed populations to uncover the dynamics of genetic change and its implications for health. Patients may benefit from insights into how their genetic backgrounds influence disease susceptibility and adaptation.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals from diverse genetic backgrounds, particularly those in admixed populations.
Not a fit: Patients with no genetic variation or those from isolated populations may not receive significant benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic factors influencing disease risk, potentially guiding personalized medicine approaches.
How similar studies have performed: Other research has shown success in understanding genetic variation and disease risk through similar computational approaches, indicating a promising avenue for further exploration.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOLDBERG, AMY — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: GOLDBERG, AMY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communicable Diseases