Understanding how genetic changes affect behavior
From association to causation: pinpointing the genetic and molecular determinants underlying natural behavioral variations
['FUNDING_OTHER'] · UNIVERSITY OF PENNSYLVANIA · NIH-11093450
This study is looking at how genes affect behavior by using fruit flies to see how different genetic changes can influence how they act, which could help us understand the biological reasons behind behavioral disorders.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11093450 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic and molecular factors that contribute to natural variations in behavior, using the fruit fly Drosophila as a model. By examining how specific genetic changes influence neural functions and behaviors, the study aims to uncover the causal links between genetics and behavior. The approach combines advanced genetic mapping techniques with automated behavioral analysis to identify the genes responsible for these variations. This research could provide insights into the biological basis of behavioral disorders and their underlying genetic causes.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals with a family history of behavioral disorders or those interested in the genetic basis of behavior.
Not a fit: Patients with purely environmental causes of behavioral issues, without any genetic component, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of the genetic factors that influence behavior, potentially informing treatments for behavioral disorders.
How similar studies have performed: Previous research has shown success in using genetic models like Drosophila to uncover the links between genetics and behavior, indicating that this approach is promising.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DING, YUN — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: DING, YUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Behavior Disorders, behavioral disorder