Understanding how genetic and immune factors contribute to pancreatic cancer development
Pancreatic Cancer Development: Genetic and Immune Regulation
This study is looking into how some cells in the pancreas change and help cause pancreatic cancer, aiming to understand the details of this process to find better ways to treat it.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10927287 on NIH RePORTER |
What this research studies
This research investigates the complex mechanisms behind pancreatic cancer, specifically focusing on how certain cells in the pancreas transform and contribute to cancer development. By studying both genetic mutations and the interactions between immune cells and cancer-associated fibroblasts, the research aims to uncover the pathways that lead to pancreatic ductal adenocarcinoma (PDAC). The team will utilize innovative mouse models and human tissue samples to explore these interactions and their implications for cancer progression.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at high risk for pancreatic cancer, such as those with a family history of the disease or specific genetic mutations.
Not a fit: Patients with advanced pancreatic cancer who are already receiving treatment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and potential therapies for pancreatic cancer, improving outcomes for patients.
How similar studies have performed: Previous research has shown promise in understanding cancer biology through similar approaches, indicating potential for success in this area.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Kim, Seung K — Stanford University
- Study coordinator: Kim, Seung K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.