Understanding how genetic and epigenetic changes contribute to cancer
Genome and Epigenome Integrity In Cancer
This study is exploring how changes in our genes and their regulation can lead to cancer, and it's designed for new scientists who want to learn how to combine these two important areas to find better ways to understand and treat cancer.
Quick facts
| Grant type | Training grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10910046 on NIH RePORTER |
What this research studies
This research focuses on the integrity of the genome and epigenome in cancer, investigating how genetic mutations and epigenetic reprogramming drive cancer development. It aims to train the next generation of scientists to bridge the gap between these two areas of study, which have historically been treated separately. By leveraging the expertise and resources at Columbia University, the program will foster innovative approaches to cancer research that could lead to new insights and treatments. The training program will involve predoctoral and postdoctoral fellows who will engage in cutting-edge research under the guidance of experienced faculty.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals diagnosed with cancer or those at high risk for developing cancer due to genetic factors.
Not a fit: Patients with non-malignant conditions or those not affected by cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for various cancers.
How similar studies have performed: Other research has shown success in exploring the connections between genome and epigenome integrity in cancer, indicating that this approach has potential for significant advancements.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Zhang, Zhiguo — Columbia University Health Sciences
- Study coordinator: Zhang, Zhiguo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.