Understanding how genetic ancestry affects health in diverse populations

The influence of genetic ancestry and population-specific epidemiology on the transferability of genomic findings to diverse and admixed populations

NIH-funded research Johns Hopkins University · NIH-10873845

This study is looking at how our genes and the environment we live in affect our health, especially for people with mixed backgrounds, to make sure that health research benefits everyone and helps reduce health differences among different groups.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10873845 on NIH RePORTER

What this research studies

This research investigates how genetic ancestry and environmental factors influence health outcomes in populations with mixed ancestry. By analyzing existing genetic data, the study aims to identify biases in genomic findings that may not apply to all groups, particularly those underrepresented in current research. The approach includes examining the interactions between genetic variants and environmental influences to better understand their combined effects on health. This work seeks to improve the transferability of genomic findings to diverse populations, ultimately aiming to reduce health inequities.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals from diverse and admixed populations who may benefit from tailored genomic medicine.

Not a fit: Patients who are solely of European descent may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more equitable healthcare by ensuring that genomic findings are applicable to all populations, improving diagnosis and treatment options.

How similar studies have performed: Other research has shown success in addressing health disparities through genomic studies, but this specific approach focusing on admixed populations is relatively novel.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.