NIH-funded research NIH-funded research

Understanding how genes move between species and their impact on evolution

Official title: Drivers and consequences of introgression in evolution

Funded at Univ of North Carolina Chapel Hill · NIH-11010408 · Data updated 2026-11-12

This study is looking at how genes move between different species of fruit flies and how this mixing helps them adapt and survive in changing environments, so we can better understand evolution and genetics.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startFebruary 7, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$504,940
NIH project number5R35GM148244-03
Project IDNIH-11010408 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals interested in evolutionary biology, genetics, and conservation efforts.

Less likely to help

Patients with no interest in genetic research or those not engaged in evolutionary studies may not receive direct benefits from this research.

What this research studies

This research investigates the process of introgression, where genes migrate between species through hybridization, particularly focusing on the fruit fly, Drosophila. By analyzing genomic data and environmental factors, the study aims to uncover how these gene exchanges influence species formation and persistence over time. The research will utilize geolocated and timestamped collections from hybrid zones to track the dynamics of introgressed alleles, providing insights into their behavior across different environments. Through this approach, the study seeks to enhance our understanding of evolutionary genetics and the role of introgression in adaptation.

Why it matters

Potential benefit: If successful, this research could provide valuable insights into the mechanisms of evolution, potentially informing conservation strategies and enhancing biodiversity.

How similar studies have gone: Previous research has shown success in understanding gene flow and hybridization in various species, indicating that this approach is grounded in established scientific inquiry.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Matute, Daniel — Univ of North Carolina Chapel Hill
  • Study coordinator: Matute, Daniel

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.