Understanding how genes influence complex traits and survival
Official title: Gene regulation and the genetic basis of complex traits
Funded at University of Kansas Lawrence · NIH-11158837 · Data updated 2026-11-12
This study is looking at how different genes can affect how well people survive and reproduce, especially by focusing on parts of our DNA that don’t directly code for proteins, and it’s designed for anyone interested in understanding the role of genetics in health and traits.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Lawrence NIH-funded |
| Lab location | 1 site (Lawrence, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $370,466 |
| NIH project number | 5R35GM154966-02 |
| Project ID | NIH-11158837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with complex traits influenced by genetic variations, particularly those related to survival and reproduction.
✕Less likely to help
Patients with conditions that are not influenced by genetic variations in complex traits may not benefit from this research.
What this research studies
This research investigates the genetic variations that contribute to differences in survival and reproduction among individuals. It focuses on complex traits influenced by multiple genetic loci and environmental factors, particularly those in non-coding regions of the genome. By integrating tissue-specific assays of gene regulation and natural population surveys, the study aims to identify specific genetic variants that affect fitness. This approach combines advanced sequencing techniques and computational methods to enhance our understanding of gene regulation and its impact on traits.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic factors influencing health and disease, potentially guiding personalized medicine.
How similar studies have gone: Previous research has shown promise in linking genetic variants to complex traits, but this study aims to advance the field by addressing existing limitations.
Where this research is happening
-
University of Kansas Lawrence
Lawrence, United States Active
Researchers
- Principal investigator: Mack, Katya — University of Kansas Lawrence
- Study coordinator: Mack, Katya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.