Understanding how genes function through a comprehensive knowledgebase
Gene Ontology Consortium and Knowledgebase
This study is working on improving a big database that helps scientists understand how genes work together, making it easier for them to find out what causes diseases and discover new ideas in biology.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11059910 on NIH RePORTER |
What this research studies
This research focuses on the Gene Ontology (GO), which is a vast knowledgebase that encodes how genes function and interact within biological systems. By utilizing modern semantic technologies, the GO knowledgebase allows for complex computational analyses that help researchers interpret large-scale molecular data. This project aims to enhance the interoperability of biological data, making it easier for researchers and clinicians to identify genetic factors in diseases. Ultimately, it seeks to facilitate the discovery of new connections and hypotheses in biological research.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with genetic disorders or those interested in the genetic basis of diseases.
Not a fit: Patients with conditions that are not influenced by genetic factors may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve our understanding of genetic contributions to diseases, leading to better diagnostic and therapeutic strategies.
How similar studies have performed: Previous research utilizing similar computational approaches in biological data analysis has shown promising results, indicating the potential for significant advancements in understanding gene functions.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Thomas, Paul D. — University of Southern California
- Study coordinator: Thomas, Paul D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.