Understanding how genes control the formation of spinal cord circuits for movement.
Genetic Control of Circuit Assembly in the Vertebrate Spinal Cord
This study is looking at how certain genes help shape the nerve connections in the spinal cord that control important movements like walking and breathing, and the findings could lead to better treatments for people with movement disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11080297 on NIH RePORTER |
What this research studies
This research investigates the genetic mechanisms that guide the development of neural circuits in the spinal cord, which are essential for controlling vital motor functions like walking, breathing, and balance. By focusing on specific genes, particularly Hox transcription factors, the study aims to uncover how these genes influence the identity and connectivity of neurons during their development. Patients may benefit from insights gained about how motor neuron circuits are formed, potentially leading to new treatments for movement disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit would include individuals with movement disorders or spinal cord injuries.
Not a fit: Patients with purely non-neurological conditions or those not affected by motor control issues may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in treating motor control disorders and improving rehabilitation strategies.
How similar studies have performed: Other research has shown success in understanding genetic influences on neural development, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Dasen, Jeremy S — New York University School of Medicine
- Study coordinator: Dasen, Jeremy S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.