Understanding how genes control cell division
How mRNA features of cell cycle genes support proper cell division
['FUNDING_OTHER'] · VIRGINIA POLYTECHNIC INST AND ST UNIV · NIH-11064887
This study is looking at how certain genes help control cell division by making proteins, and it aims to understand these processes better to improve our knowledge of cancer and other diseases linked to problems with cell growth.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VIRGINIA POLYTECHNIC INST AND ST UNIV (nih funded) |
| Locations | 1 site (BLACKSBURG, UNITED STATES) |
| Trial ID | NIH-11064887 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which genes responsible for cell cycle regulation produce proteins that drive cell division. It focuses on the different strategies that genes use to create messenger RNA and proteins, which are crucial for the proper functioning of the cell cycle machinery. By analyzing how these strategies affect protein levels and interactions, the research aims to uncover the underlying rules that govern cell division. This knowledge could lead to better insights into cancer and other diseases related to cell cycle dysregulation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic predispositions to cancers or those affected by conditions related to cell cycle regulation.
Not a fit: Patients with conditions unrelated to cell cycle regulation or those not affected by cancer genetics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for cancers and other conditions related to cell division errors.
How similar studies have performed: Previous research has shown success in understanding gene expression strategies in other contexts, suggesting potential for breakthroughs in this area as well.
Where this research is happening
BLACKSBURG, UNITED STATES
- VIRGINIA POLYTECHNIC INST AND ST UNIV — BLACKSBURG, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAUF, SILKE — VIRGINIA POLYTECHNIC INST AND ST UNIV
- Study coordinator: HAUF, SILKE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: cancer genetics, Cancers