Understanding how genes control cell division
Official title: How mRNA features of cell cycle genes support proper cell division
Funded at Virginia Polytechnic Inst and St Univ · NIH-11064887 · Data updated 2026-11-12
This study is looking at how certain genes help control cell division by making proteins, and it aims to understand these processes better to improve our knowledge of cancer and other diseases linked to problems with cell growth.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Polytechnic Inst and St Univ NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project start | June 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $376,607 |
| NIH project number | 5R35GM149565-03 |
| Project ID | NIH-11064887 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with genetic predispositions to cancers or those affected by conditions related to cell cycle regulation.
✕Less likely to help
Patients with conditions unrelated to cell cycle regulation or those not affected by cancer genetics may not benefit from this research.
What this research studies
This research investigates the mechanisms by which genes responsible for cell cycle regulation produce proteins that drive cell division. It focuses on the different strategies that genes use to create messenger RNA and proteins, which are crucial for the proper functioning of the cell cycle machinery. By analyzing how these strategies affect protein levels and interactions, the research aims to uncover the underlying rules that govern cell division. This knowledge could lead to better insights into cancer and other diseases related to cell cycle dysregulation.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for cancers and other conditions related to cell division errors.
How similar studies have gone: Previous research has shown success in understanding gene expression strategies in other contexts, suggesting potential for breakthroughs in this area as well.
Where this research is happening
-
Virginia Polytechnic Inst and St Univ
Blacksburg, United States Active
Researchers
- Principal investigator: Hauf, Silke — Virginia Polytechnic Inst and St Univ
- Study coordinator: Hauf, Silke
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.