Understanding how genes control cell development and shape in a new mollusc model.
Building a gene regulatory network-based model for cell fate specification and morphogenesis using a new mollusc model.
This study is looking at how genes control the way cells develop and shape themselves in molluscs, which are a type of animal, to help us understand how different body types have evolved over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10725033 on NIH RePORTER |
What this research studies
This research investigates how gene regulatory networks (GRNs) influence cell fate specification and morphogenesis in molluscs, a group of animals that has not been extensively studied in this context. By analyzing the genetic connections that dictate how cells develop and differentiate, the project aims to uncover the evolutionary changes in these networks. The approach involves detailed comparisons of cell lineages and developmental processes at a single-cell level, providing insights into the diversity of body plans in molluscs. This could enhance our understanding of fundamental biological processes that apply to a wide range of organisms.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals interested in the genetic and developmental mechanisms underlying various biological forms and functions.
Not a fit: Patients with conditions unrelated to genetic or developmental biology may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding developmental biology and evolutionary processes, potentially informing medical and biological applications.
How similar studies have performed: While the approach of using molluscs for gene regulatory network analysis is relatively novel, similar studies in other model organisms have shown promising results in understanding developmental processes.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Lyons, Deirdre C — University of California, San Diego
- Study coordinator: Lyons, Deirdre C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.