Understanding how genes control behavior in tiny worms
Genetic Analysis of Nematode Egg Laying and Co-regulated Behavioral Systems
['FUNDING_R01'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-11087547
This project explores how genes guide the actions of a small worm, aiming to uncover basic biological rules that might apply to human health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11087547 on ClinicalTrials.gov |
What this research studies
Researchers are studying the simple nervous system of a tiny worm called C. elegans to learn how genes direct its behaviors, like egg-laying and movement. By looking at how the worm reacts to things like low oxygen and light, we can learn about fundamental biological processes. This work helps us understand how animals, including humans, respond to their environment and stress. The goal is to map out the genetic, cellular, and neural pathways involved in these responses.
Who could benefit from this research
Good fit: Patients interested in the fundamental genetic and neurological underpinnings of behavior and stress responses in living organisms may find this research relevant.
Not a fit: Patients seeking immediate clinical treatments or direct human intervention will not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this foundational work could reveal basic mechanisms of behavior and stress response that are relevant to many human disorders.
How similar studies have performed: This project builds upon decades of successful research using C. elegans as a model to understand fundamental biological processes.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HORVITZ, H ROBERT — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: HORVITZ, H ROBERT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.