Understanding how genes are regulated in individual cells
Decoding the Noncoding Regulatory Genome with Super-resolution via Single-cell Multiomics Integration
This study is looking at how genes work differently in individual cells, which could help us understand diseases better and lead to more personalized treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10867378 on NIH RePORTER |
What this research studies
This research investigates the complex ways in which genes are regulated within individual cells, focusing on how these processes can differ from one cell to another. By utilizing advanced technologies that analyze single cells, the project aims to create detailed models that represent the unique regulatory mechanisms at play in various cell types. The approach involves integrating multiple types of data to better understand how dysregulation can lead to diseases. Patients may benefit from insights gained about their specific cellular regulation, potentially leading to more personalized treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals over 21 years old who may have conditions related to gene regulation dysregulation.
Not a fit: Patients who are under 21 years old or do not have conditions related to gene regulation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for a range of diseases by understanding individual cellular regulation.
How similar studies have performed: While the integration of single-cell multiomics is a relatively novel approach, similar studies have shown promise in advancing our understanding of gene regulation.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Zhang, Jing — University of California-Irvine
- Study coordinator: Zhang, Jing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.